Photo from wikipedia
A direct oxidative esterification of alpha-amino carbonyl compounds by two kinds of hydroperoxides, for the synthesis of alpha-keto esters has been developed. The reaction shows broad substrates scope and good… Click to show full abstract
A direct oxidative esterification of alpha-amino carbonyl compounds by two kinds of hydroperoxides, for the synthesis of alpha-keto esters has been developed. The reaction shows broad substrates scope and good functional group tolerance, even for the synthesis of bulkyl esters, and is free of metal catalysts and external additives. Notably, the inhibitor of protein tyrosine phosphatases (PTPases) could be successfully synthesized with our protocol.
Keywords:
oxidative esterification;
keto esters;
amino carbonyl;
carbonyl compounds
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!