A TEMPO‐oxidized method has been developed for the synthesis of bis(indolyl)‐methane derivatives by the cross‐dehydrogenative coupling between C(sp3)–H of para‐cresol derivatives and C(sp2)‐H of indoles in moderate yields under aqueous… Click to show full abstract
A TEMPO‐oxidized method has been developed for the synthesis of bis(indolyl)‐methane derivatives by the cross‐dehydrogenative coupling between C(sp3)–H of para‐cresol derivatives and C(sp2)‐H of indoles in moderate yields under aqueous conditions. This approach has significant advantages in avoiding prefunctionalization, using water as the solvent and tolerating various functional groups.
Keywords:
cross dehydrogenative;
dehydrogenative coupling;
synthesis bis;
bis indolyl
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!