A convenient and efficient protocol for the synthesis of 3,3‐dialkylated oxindoles through photocatalytic aerobic radical‐cascade alkylation/cyclization of N‐arylacrylamides with the alkyl radicals generated from simple alkanes is described. This method… Click to show full abstract
A convenient and efficient protocol for the synthesis of 3,3‐dialkylated oxindoles through photocatalytic aerobic radical‐cascade alkylation/cyclization of N‐arylacrylamides with the alkyl radicals generated from simple alkanes is described. This method features a broad substrate scope, inexpensive alkyl radical precursors, simple conditions and good yields.
Keywords:
cyclization arylacrylamides;
simple alkanes;
alkylation cyclization;
cascade alkylation
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2024
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Journal Title: Asian Journal of Organic Chemistry
Year Published: 2024
Link to full text (if available)
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recommendations!