Selected functionalized saturated azaheterocycles have been prepared by ring expansion from their unsaturated counterpart or using substituted cycloalkenes involving oxidative ring opening/ring closing by reductive amination. Studies have been conducted… Click to show full abstract
Selected functionalized saturated azaheterocycles have been prepared by ring expansion from their unsaturated counterpart or using substituted cycloalkenes involving oxidative ring opening/ring closing by reductive amination. Studies have been conducted regarding the outcome of the transformations, the effect of the ring strain, and stereocontrol. The synthesized amino acid derivatives possessing either an aryl or fluorine element in their structure might be relevant building blocks for foldamer chemistry.
Journal Title: Asian Journal of Organic Chemistry
Year Published: 2025
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