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Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective symptomatic therapy for motor deficits in Parkinson's disease (PD). An additional, disease‐modifying effect has been suspected from… Click to show full abstract
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a highly effective symptomatic therapy for motor deficits in Parkinson's disease (PD). An additional, disease‐modifying effect has been suspected from studies in toxin‐based PD animal models, but these models do not reflect the molecular pathology and progressive nature of PD that would be required to evaluate a disease‐modifying action. Defining a disease‐modifying effect could radically change the way in which DBS is used in PD.
Keywords:
deep brain;
disease;
parkinson disease;
subthalamic nucleus;
brain stimulation
Journal Title: Annals of Neurology
Year Published: 2017
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!