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Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in peripheral blood. Various diseases causing neuronal damage… Click to show full abstract
Neurofilament light chains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low concentrations in peripheral blood. Various diseases causing neuronal damage have resulted in elevated CSF concentrations. We explored the value of an ultrasensitive single‐molecule array (Simoa) serum NfL (sNfL) assay in multiple sclerosis (MS).
Keywords:
neuronal damage;
neurofilament light;
multiple sclerosis
Journal Title: Annals of Neurology
Year Published: 2017
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2017
Link to full text (if available)
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recommendations!