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Cortical spreading depression (CSD) has long been implicated in migraine attacks with aura. The process by which CSD, a cortical event that occurs within the blood–brain barrier (BBB), results in… Click to show full abstract
Cortical spreading depression (CSD) has long been implicated in migraine attacks with aura. The process by which CSD, a cortical event that occurs within the blood–brain barrier (BBB), results in nociceptor activation outside the BBB is likely mediated by multiple molecules and cells. The objective of this study was to determine whether CSD activates immune cells inside the BBB (pia), outside the BBB (dura), or in both, and if so, when.
Keywords:
activation pial;
cortical spreading;
spreading depression;
bbb
Journal Title: Annals of Neurology
Year Published: 2018
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!