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N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox modulatory compound currently in trials for many neurological and psychiatric disorders. Although generically labeled as an “antioxidant,” poor understanding of its site(s)… Click to show full abstract
N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox modulatory compound currently in trials for many neurological and psychiatric disorders. Although generically labeled as an “antioxidant,” poor understanding of its site(s) of action is a barrier to its use in neurological practice. Here, we examined the efficacy and mechanism of action of NAC in rodent models of hemorrhagic stroke.
Keywords:
hemorrhagic stroke;
acetylcysteine targets;
lipoxygenase derived;
toxic lipids;
targets lipoxygenase;
derived toxic
Journal Title: Annals of Neurology
Year Published: 2018
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2018
Link to full text (if available)
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recommendations!