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Despite decades of epilepsy research, 30% of focal epilepsies remain resistant to antiseizure drugs, with effective drug development impeded by lack of understanding on how seizures are initiated. Here, we… Click to show full abstract
Despite decades of epilepsy research, 30% of focal epilepsies remain resistant to antiseizure drugs, with effective drug development impeded by lack of understanding on how seizures are initiated. Here, we report the mechanism of seizure onset relevant to most seizures that are characteristic of focal epilepsies.
Keywords:
adenine dinucleotide;
nicotinamide adenine;
dinucleotide phosphate;
phosphate oxidase;
activation nicotinamide;
oxidase primary
Journal Title: Annals of Neurology
Year Published: 2019
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!