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Coffee Consumption and Risk of Stroke: A Mendelian Randomization Study

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Observational epidemiological studies have reported a relationship between coffee intake and risk of stroke. However, evidence for this association is inconsistent, and it remains uncertain whether the association is causal… Click to show full abstract

Observational epidemiological studies have reported a relationship between coffee intake and risk of stroke. However, evidence for this association is inconsistent, and it remains uncertain whether the association is causal or due to confounding or reverse causality. To clarify this relationship, we adopted a Mendelian randomization (MR) approach to evaluate the effects of coffee consumption on the risk of stroke and its subtypes.

Keywords: mendelian randomization; coffee consumption; consumption risk; risk stroke; coffee

Journal Title: Annals of Neurology
Year Published: 2020

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