LAUSR

diction such as underlying etiology. However, we would like to emphasize that the stroke severity on admission and the treatment regimen may similarly have major influence on outcome after childhood stroke. Recently, the Save ChildS Study, including 73 children with large vessel occlusion ischemic stroke who underwent endovascular thrombectomy at 27 centers in Europe and the United States, has provided the first evidence that endovascular thrombectomy in children may provide similar benefits when compared to adults. In this study, the majority of patients had good outcomes, with a median modified Rankin Scale (mRS) score of 1.0 (interquartile range [IQR] = 0.2–2.0) and a median Pediatric Stroke Outcome Measure (PSOM) score of 1.0 (IQR = 0–2.0) at discharge. Neurological outcomes further improved to an mRS of 1.0 (IQR = 0–1.6) after 6 months and 1.0 (IQR = 0–1.0) after 24 months and a PSOM of 0.5 (IQR = 0–1.0) 6 and 24 months after the intervention. Analyses grouped by age suggested that the mRS score at discharge was higher in children aged 0 to 6 years (3.5; IQR = 1.0–5.1) than in the whole study cohort including all age groups (1.0, IQR = 0.2–2.0). Whereas one might think this may be attributed to the selection of thrombectomy devices, a post hoc analysis revealed that neurological outcomes were not associated with any specific device selection. The cohorts in both studies likely differ greatly, as the Save ChildS Study only included patients with large artery occlusions. However, it would be interesting to see more information on stroke severity at admission and selection of therapies in the different age groups included in the article by Felling and colleagues.