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Lesion Age Imaging in Acute Stroke: Water Uptake in CT Versus DWI‐FLAIR Mismatch

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In acute ischemic stroke with unknown time of onset, magnetic resonance (MR)‐based diffusion‐weighted imaging (DWI) and fluid‐attenuated inversion recovery (FLAIR) estimates lesion age to guide intravenous thrombolysis. Computed tomography (CT)‐based… Click to show full abstract

In acute ischemic stroke with unknown time of onset, magnetic resonance (MR)‐based diffusion‐weighted imaging (DWI) and fluid‐attenuated inversion recovery (FLAIR) estimates lesion age to guide intravenous thrombolysis. Computed tomography (CT)‐based quantitative net water uptake (NWU) may be a potential alternative. The purpose of this study was to directly compare CT‐based NWU to magnetic resonance imaging (MRI) at identifying patients with lesion age < 4.5 hours from symptom onset.

Keywords: age; lesion age; flair; dwi; water uptake; stroke

Journal Title: Annals of Neurology
Year Published: 2020

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