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The Effect of SMN Gene Dosage on ALS Risk and Disease Severity

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The role of the survival of motor neuron (SMN) gene in amyotrophic lateral sclerosis (ALS) is unclear, with several conflicting reports. A decisive result on this topic is needed, given… Click to show full abstract

The role of the survival of motor neuron (SMN) gene in amyotrophic lateral sclerosis (ALS) is unclear, with several conflicting reports. A decisive result on this topic is needed, given that treatment options are available now for SMN deficiency.

Keywords: smn gene; gene dosage; als risk; effect smn; gene; dosage als

Journal Title: Annals of Neurology
Year Published: 2021

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