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The encephalitis associated with antibodies against contactin‐associated proteinlike 2 (CASPR2) is presumably antibody‐mediated, but the antibody effects and whether they cause behavioral alterations are not well known. Here, we used… Click to show full abstract
The encephalitis associated with antibodies against contactin‐associated proteinlike 2 (CASPR2) is presumably antibody‐mediated, but the antibody effects and whether they cause behavioral alterations are not well known. Here, we used a mouse model of patients' immunoglobulin G (IgG) transfer and super‐resolution microscopy to demonstrate the antibody pathogenicity.
Keywords:
alter memory;
antibodies reversibly;
caspr2;
caspr2 antibodies;
reversibly alter;
human caspr2
Journal Title: Annals of Neurology
Year Published: 2022
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2022
Link to full text (if available)
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recommendations!