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Accumulation of α‐synuclein (α‐syn) in neurons is a prominent feature of Parkinson's disease (PD). Recently, researchers have considered that extracellular vesicles (EVs) may play an important role in protein exportation… Click to show full abstract
Accumulation of α‐synuclein (α‐syn) in neurons is a prominent feature of Parkinson's disease (PD). Recently, researchers have considered that extracellular vesicles (EVs) may play an important role in protein exportation and propagation, and α‐syn‐containing EVs derived from the central nervous system (CNS) have been detected in peripheral blood. However, mechanistic insights into CNS‐derived EVs have not been well‐described.
Keywords:
exosomes aggravate;
derived exosomes;
disease;
parkinson disease;
disease derived;
aggravate neuropathology
Journal Title: Annals of Neurology
Year Published: 2022
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Journal Title: Annals of Neurology
Year Published: 2022
Link to full text (if available)
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recommendations!