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Elevated vascular risk and beta‐amyloid (Aβ) burden have been synergistically associated with cognitive decline in preclinical Alzheimer's disease (AD), although the underlying mechanisms remain unclear. We examined whether accelerated longitudinal… Click to show full abstract
Elevated vascular risk and beta‐amyloid (Aβ) burden have been synergistically associated with cognitive decline in preclinical Alzheimer's disease (AD), although the underlying mechanisms remain unclear. We examined whether accelerated longitudinal tau accumulation mediates the vascular risk‐Aβ interaction on cognitive decline.
Keywords:
mediates synergistic;
tau mediates;
vascular risk;
cognitive decline
Journal Title: Annals of Neurology
Year Published: 2022
Link to full text (if available)
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Journal Title: Annals of Neurology
Year Published: 2022
Link to full text (if available)
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recommendations!