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A Subpopulation of Spikes Predicts Successful Epilepsy Surgery Outcome

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Epileptic spikes are the traditional interictal electroencephalographic (EEG) biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ), they are given only moderate attention in presurgical evaluation.… Click to show full abstract

Epileptic spikes are the traditional interictal electroencephalographic (EEG) biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ), they are given only moderate attention in presurgical evaluation. This study aims to demonstrate that it is possible to identify specific spike features in intracranial EEG that optimally define the EZ and predict surgical outcome.

Keywords: epilepsy surgery; outcome; predicts successful; successful epilepsy; subpopulation spikes; spikes predicts

Journal Title: Annals of Neurology
Year Published: 2022

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