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Role of Enlarged Perivascular Space in the Temporal Lobe in Cerebral Amyloidosis

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Although growing evidence suggests that perivascular space (PVS) serves as a clearance route for amyloid and tau, the association between enlarged PVS (EPVS) and Alzheimer disease is highly inconsistent across… Click to show full abstract

Although growing evidence suggests that perivascular space (PVS) serves as a clearance route for amyloid and tau, the association between enlarged PVS (EPVS) and Alzheimer disease is highly inconsistent across studies. As the conventional visual rating systems for EPVS were insufficient to predict amyloid/tau/neurodegeneration (A/T/N) status, we developed a new rating scale for EPVS located in the temporal lobe (T‐EPVS).

Keywords: temporal lobe; enlarged perivascular; role enlarged; perivascular space

Journal Title: Annals of Neurology
Year Published: 2023

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