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Rapid Eye Movement Sleep, Neurodegeneration, and Amyloid Deposition in Aging

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Rapid eye movement (REM) sleep is markedly altered in Alzheimer's disease (AD), and its reduction in older populations is associated with AD risk. However, little is known about the underlying… Click to show full abstract

Rapid eye movement (REM) sleep is markedly altered in Alzheimer's disease (AD), and its reduction in older populations is associated with AD risk. However, little is known about the underlying brain mechanisms. Our objective was to investigate the relationships between REM sleep integrity and amyloid deposition, gray matter volume, and perfusion in aging.

Keywords: eye movement; rapid eye; amyloid deposition

Journal Title: Annals of Neurology
Year Published: 2023

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