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Bradykinesia and Its Progression Are Related to Interhemispheric Beta Coherence

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Bradykinesia is the major cardinal motor sign of Parkinson disease (PD), but its neural underpinnings are unclear. The goal of this study was to examine whether changes in bradykinesia following… Click to show full abstract

Bradykinesia is the major cardinal motor sign of Parkinson disease (PD), but its neural underpinnings are unclear. The goal of this study was to examine whether changes in bradykinesia following long‐term subthalamic nucleus (STN) deep brain stimulation (DBS) are linked to local STN beta (13–30 Hz) dynamics or a wider bilateral network dysfunction.

Keywords: interhemispheric beta; related interhemispheric; beta; bradykinesia progression; beta coherence; progression related

Journal Title: Annals of Neurology
Year Published: 2023

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