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Facile synthesis of indene and fluorene derivatives through AlCl3‐catalyzed cyclization of in situ formed iminium ions

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A simple AlCl3-catalyzed condensation/cyclization cascade process between aldehydes and sulfonamide is reported, in which two new bonds and one five-membered ring are simultaneously formed with water as the byproduct. This… Click to show full abstract

A simple AlCl3-catalyzed condensation/cyclization cascade process between aldehydes and sulfonamide is reported, in which two new bonds and one five-membered ring are simultaneously formed with water as the byproduct. This method provides a rapid access to indenamine and 9-aminofluorene derivatives. Additionally, these products can be transformed into corresponding indanones and fluorenones under the developed conditions.

Keywords: indene fluorene; facile synthesis; cyclization; fluorene derivatives; synthesis indene; alcl3 catalyzed

Journal Title: Applied Organometallic Chemistry
Year Published: 2017

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