In this research, an effective procedure for the one‐pot construction of new quinazoline analogs using chloroacetic acid–immobolized nanocobaltferrite (nano‐CoFe2O4@SiO2@CPTES‐[(Ph₂PCH₂)₂‐CH2CO2H]2+2Cl−) as an efficient novel magnetic nanocatalyst under ultrasound irradiation at 80°C… Click to show full abstract
In this research, an effective procedure for the one‐pot construction of new quinazoline analogs using chloroacetic acid–immobolized nanocobaltferrite (nano‐CoFe2O4@SiO2@CPTES‐[(Ph₂PCH₂)₂‐CH2CO2H]2+2Cl−) as an efficient novel magnetic nanocatalyst under ultrasound irradiation at 80°C was presented. Chloroacetic acid–immobilized nanocobferrite was characterized by FT‐IR, XRD, FE‐SEM, TEM, EDX, TGA, VSM, and ICP‐mass analyses. Furthermore, the nanocatalyst could be comfortably isolated via magnetic attraction and recycled at least five times without remarkable loss of its catalytic activity. Additionally, in this protocol, quinazoline analogs were screened for their antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus. The results showed that quinazolines 4a, 4b, 4c, 4d, and 4g had good antibacterial activity toward Pseudomonas aeruginosa and Staphylococcus aureus.
Journal Title: Applied Organometallic Chemistry
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!