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Anti‐inflammatory activity of pyridazinones: A review

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The pyridazinone core has emerged as a leading structure for fighting inflammation, with low ulcerogenic effects. Moreover, easy functionalization of various ring positions of the pyridazinone core structure makes it… Click to show full abstract

The pyridazinone core has emerged as a leading structure for fighting inflammation, with low ulcerogenic effects. Moreover, easy functionalization of various ring positions of the pyridazinone core structure makes it an attractive synthetic and therapeutic target for the design and synthesis of anti‐inflammatory agents. The present review surveys the recent advances of pyridazinone derivatives as potential anti‐inflammatory agents to provide insights into the rational design of more effective anti‐inflammatory pyridazinones.

Keywords: activity pyridazinones; anti inflammatory; inflammatory activity; inflammatory; pyridazinones review

Journal Title: Archiv der Pharmazie
Year Published: 2022

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