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Reduced GABA and altered somatosensory function in children with autism spectrum disorder

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Background: Abnormal responses to tactile stimuli are a common feature of autism spectrum disorder (ASD). Several lines of evidence suggest that GABAergic function, which has a crucial role in tactile… Click to show full abstract

Background: Abnormal responses to tactile stimuli are a common feature of autism spectrum disorder (ASD). Several lines of evidence suggest that GABAergic function, which has a crucial role in tactile processing, is altered in ASD. In this study, we determine whether in vivo GABA levels are altered in children with ASD, and whether alterations in GABA levels are associated with abnormal tactile function in these children.

Keywords: function children; spectrum disorder; children autism; function; autism spectrum

Journal Title: Autism Research
Year Published: 2017

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