LAUSR

Highly sensitive silica-Alumina (Si-Al) modified capacitive non-faradaic glucose biosensor was introduced to monitor the gestational diabetes. Glucose oxidase (GOx) was attached on Si-Al electrode surface as the probe through amine-modification followed by glutaraldehyde premixed GOx as aldehyde-amine chemistry. This Si-Al (∼50 nm) modified electrode surface has increased the current flow upon binding of GOx with glucose. Capacitance values were increased by increasing the glucose concentrations. Mean capacitance value was plotted and found the detection limit as 0.03 mg/mL with the regression co-efficient value, R² = 0.9782 [y = 0.8391x + 1.338] on the linear ranges between 0.03 and 1 mg/mL. Further, biofouling experiment with fructose and galactose did not increase the capacitance, indicating the specific glucose detection. This Si-Al modified capacitance sensor detect a lower level of glucose presence and helps in monitoring the gestational diabetes. This article is protected by copyright. All rights reserved.