LAUSR

A novel bio-nanocomposite was developed by incorporating the extracted nano chitosan from shrimp wastes with Schiff base cobalt complex (Chit@Co complex(. The phytosynthesis of Chit@Co complex/Ag bio-nanocomposite was designed utilizing Chit@Co complex at the present of Ferulago angulate extraction and characterized by AFM, SEM, EDAX, TEM, FT-IR, and elemental analysis. The radioprotective application of this bio-nanocomposite on human lymphocyte cells was evaluated using micronucleus (MN) assay. Total antioxidant activities of it were evaluated using FRAP and DPPH assay. Chit@Co complex/Ag bio-nanocomposite significantly decreased the frequency of micronuclei in human lymphocytes exposed to ionization irradiation (IR). The highest protection was observed at 200 μg/ml. Also, maximum antioxidant activities of bio-nanocomposite were provided at the same dose. This data exhibits the radioprotective effect of a bio-nanocomposite based on wastes of living organisms can be an excellent radioprotective agent which can protect the normal cells of human against the genetic damage by IR. This article is protected by copyright. All rights reserved.