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Pharmacokinetic and pharmacodynamic modelling of continuous erythropoiesis receptor activator in children: A comprehensive analysis and real‐world data validation

To further assess the pharmacokinetic/pharmacodynamic characteristics of methoxy polyethylene glycol‐epoetin β (continuous erythropoiesis receptor activator; C.E.R.A.) in children with chronic kidney disease (CKD) aged 3 months to 18 years undergoing different dialysis… Click to show full abstract

To further assess the pharmacokinetic/pharmacodynamic characteristics of methoxy polyethylene glycol‐epoetin β (continuous erythropoiesis receptor activator; C.E.R.A.) in children with chronic kidney disease (CKD) aged 3 months to 18 years undergoing different dialysis modalities and receiving intravenous/subcutaneous doses, compared with adults.

Keywords: erythropoiesis receptor; continuous erythropoiesis; receptor activator; activator children; pharmacokinetic pharmacodynamic

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2025

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