LAUSR

This article reports on a standard set of developmental and reproductive toxicity studies with molindone. I submit that the presented data does not support the major conclusion as stated in the Abstract (“Molindone was not developmentally toxic in rats or rabbits at 69X and 6X clinical exposures, confirming the reproductive safety of molindone”). Indeed, the rat range-finding and definitive EFD toxicity studies showed no indications of developmental toxicity based on presented data. However, in the prenatal/postnatal rat study the following were clear signals of developmental toxicity.