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Development of Ionic Liquid-Water-Based Thermomorphic Solvent (TMS)-Systems for Biocatalytic Reactions.

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The applicability of ionic liquid-water-based thermo-morphic solvent (TMS)-systems with an upper critical solution temperature (UCST) for homogeneous biocatalysis was investigated. Cholinium- and imidazolium based ionic liquids were used to facilitate… Click to show full abstract

The applicability of ionic liquid-water-based thermo-morphic solvent (TMS)-systems with an upper critical solution temperature (UCST) for homogeneous biocatalysis was investigated. Cholinium- and imidazolium based ionic liquids were used to facilitate a temperature-depended phase change, which can be easily fine-tuned by adding salts or polar organic solvents. Within the TMS-system, a high enzymatic activity and subsequently full conversion was achieved in the intermittent monophasic reaction system of the TMS-system, therefore the biocatalyst can be easily recycled after separating the phases at lower temperatures. This article is protected by copyright. All rights reserved.

Keywords: ionic liquid; tms systems; solvent tms; tms; liquid water; water based

Journal Title: Biotechnology journal
Year Published: 2019

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