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Retrotransposons, such as long interspersed element‐1 (LINE‐1), can copy themselves to other genomic loci via a transposition event (termed retrotransposition). Retrotransposons, therefore, have potential use as an efficient gene delivery… Click to show full abstract
Retrotransposons, such as long interspersed element‐1 (LINE‐1), can copy themselves to other genomic loci via a transposition event (termed retrotransposition). Retrotransposons, therefore, have potential use as an efficient gene delivery tool to integrate multiple copies of a target gene into a host genome. Here, we developed a retrotransposon vector based on LINE‐1 that achieves target gene integration of multiple transgene copies.
Keywords:
vectors mediate;
line;
mediate recombinant;
line vectors;
retrotransposition;
gene
Journal Title: Biotechnology Journal
Year Published: 2021
Link to full text (if available)
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Journal Title: Biotechnology Journal
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!