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Multienzyme Cascade Synthesis of Rare Sugars From Glycerol in Bacillus subtilis

Rare sugars are valuable and unique monosaccharides extensively utilized in the food, cosmetics, and pharmaceutical industries. Considering the high purification costs and the complex processes of enzymatic synthesis, whole‐cell conversion… Click to show full abstract

Rare sugars are valuable and unique monosaccharides extensively utilized in the food, cosmetics, and pharmaceutical industries. Considering the high purification costs and the complex processes of enzymatic synthesis, whole‐cell conversion has emerged as a significantly important alternative. The Escherichia coli strain was initially used in whole‐cell synthesis of rare sugars. However, its pathogenic nature poses limitations to its widespread applications. Consequently, there is an urgent need to explore biologically safe strains for the efficient production of rare sugars.

Keywords: rare sugars; synthesis rare; cascade synthesis; synthesis; sugars glycerol; multienzyme cascade

Journal Title: Biotechnology Journal
Year Published: 2024

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