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Morphological lymphocytic reaction, patient prognosis and PD‐1 expression after surgical resection for oesophageal cancer

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Immune checkpoint inhibitors, such as antibody against programmed cell death protein (PD‐1), have demonstrated antitumour effects in patients with malignancies, including oesophageal cancer. A lymphocytic reaction observed by pathological examination… Click to show full abstract

Immune checkpoint inhibitors, such as antibody against programmed cell death protein (PD‐1), have demonstrated antitumour effects in patients with malignancies, including oesophageal cancer. A lymphocytic reaction observed by pathological examination is a manifestation of the host immune response to tumour cells. It was hypothesized that a stronger lymphocytic reaction to tumours might be associated with favourable prognosis in oesophageal cancer.

Keywords: lymphocytic reaction; prognosis; oesophageal cancer

Journal Title: British Journal of Surgery
Year Published: 2019

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