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Astrocytes and radial glia‐like cells, but not neurons, display a nonapoptotic increase in caspase‐3 expression following exercise

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Exercise induces plasticity in the hippocampus, which includes increases in neurogenesis, the proliferation of new neurons, and angiogenesis, the sprouting of new capillaries from preexisting blood vessels. Following exercise, astrocytes… Click to show full abstract

Exercise induces plasticity in the hippocampus, which includes increases in neurogenesis, the proliferation of new neurons, and angiogenesis, the sprouting of new capillaries from preexisting blood vessels. Following exercise, astrocytes also undergo morphological changes that parallel the events occurring in the neurovascular system. Interestingly, there have also been reports of apoptosis in the hippocampus following aerobic exercise. This experiment aimed to identify which population of hippocampal cells undergoes apoptosis after an acute bout of exercise.

Keywords: radial glia; following exercise; glia like; exercise astrocytes; exercise; astrocytes radial

Journal Title: Brain and Behavior
Year Published: 2018

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