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Traumatic brain injury (TBI) has ranked as one of the leading causes of disability and death in the world. The neuroinflammation mediated by signal transducer and activator of transcription 3… Click to show full abstract
Traumatic brain injury (TBI) has ranked as one of the leading causes of disability and death in the world. The neuroinflammation mediated by signal transducer and activator of transcription 3 (STAT3) signaling during the progression of TBI leads to long‐term neurodegeneration. Ring finger protein 6 (RNF‐6) is an E3 ubiquitin ligase and can regulate the activity of STAT3 signaling pathway by targeting its inhibitors. However, the mechanism underlying this process in TBI remains poorly understood.
Keywords:
traumatic brain;
inhibition rnf6;
brain injury;
brain;
stat3 signaling
Journal Title: Brain and Behavior
Year Published: 2020
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Journal Title: Brain and Behavior
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!