Sickle cell disease (SCD) is a hereditary blood disorder in which the oxygen‐carrying hemoglobin molecule in red blood cells is abnormal. SCD patients are at increased risks for strokes and… Click to show full abstract
Sickle cell disease (SCD) is a hereditary blood disorder in which the oxygen‐carrying hemoglobin molecule in red blood cells is abnormal. SCD patients are at increased risks for strokes and neurocognitive deficit, even though neurovascular screening and treatments have lowered the rate of overt strokes. Tract‐specific analysis (TSA) is a statistical method to evaluate microstructural WM damage in neurodegenerative disorders, using diffusion tensor imaging (DTI).
               
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