Photo by sxy_selia from unsplash
PCNSL is a rare extranodal NHL with poor prognosis. Tumorigenesis has been associated with hyperactivation of BCR downstream and NFkB pathways. We studied the prognosis of the relative expression profile… Click to show full abstract
PCNSL is a rare extranodal NHL with poor prognosis. Tumorigenesis has been associated with hyperactivation of BCR downstream and NFkB pathways. We studied the prognosis of the relative expression profile of target genes of NFkB pathway (MYC, BCL2), the essential transcriptional regulator in hematopoiesis LMO2, the checkpoint regulation pathway MGMT, the transcription factor POU2F1, the immune checkpoint gene PDCD1, and the proto‐oncogene and transcriptional repressor gene BCL6 and its proteins in PCNSL.
Keywords:
genetic prognostic;
new genetic;
central nervous;
prognostic biomarkers;
primary central;
biomarkers primary
Journal Title: Brain and Behavior
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Brain and Behavior
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!