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Structural impairments in hippocampal and occipitotemporal networks specifically contribute to decline in place and face category processing but not to other visual object categories in healthy aging

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Functional neuroimaging studies have identified a set of nodes in the occipital–temporal cortex that preferentially respond to faces in comparison with other visual objects. By contrast, the processing of places… Click to show full abstract

Functional neuroimaging studies have identified a set of nodes in the occipital–temporal cortex that preferentially respond to faces in comparison with other visual objects. By contrast, the processing of places seems to rely on parahippocampal cortex and structures heavily implicated in memory (e.g., the hippocampus). It has been suggested that human aging leads to decreased neural specialization of core face and place processing areas and impairments in face and place perception.

Keywords: structural impairments; hippocampal occipitotemporal; occipitotemporal networks; place; face; impairments hippocampal

Journal Title: Brain and Behavior
Year Published: 2021

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