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Maternal immune activation alters adult behavior, intestinal integrity, gut microbiota and the gut inflammation

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Schizophrenia is characterized by several core behavioral features, in which the gastrointestinal symptoms are frequently reported. Maternal immune activation (MIA) has been developed in a rodent model to study neurodevelopmental… Click to show full abstract

Schizophrenia is characterized by several core behavioral features, in which the gastrointestinal symptoms are frequently reported. Maternal immune activation (MIA) has been developed in a rodent model to study neurodevelopmental disorders such as schizophrenia. However, the changes in the gut environment of MIA rats remain largely unknown.

Keywords: immune activation; maternal immune; gut; alters adult; activation alters

Journal Title: Brain and Behavior
Year Published: 2021

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