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Histone deacetylase HDAC2 regulates microRNA‐125a expression in neuroblastoma

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Neuroblastoma (NB) is an infrequent childhood malignancy of the peripheral sympathetic nervous system and is accountable for about 10% of pediatric tumors. microRNA (miR)‐125a has been implicated to serve as… Click to show full abstract

Neuroblastoma (NB) is an infrequent childhood malignancy of the peripheral sympathetic nervous system and is accountable for about 10% of pediatric tumors. microRNA (miR)‐125a has been implicated to serve as a tumor suppressor in various cancers. Herein, we set out to ascertain whether miR‐125a exerts antitumor effects in NB.

Keywords: deacetylase hdac2; regulates microrna; microrna 125a; hdac2 regulates; 125a expression; histone deacetylase

Journal Title: Brain and Behavior
Year Published: 2022

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