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Stroke is a devastating event and a huge public health concern worldwide. Apremilast (APR) is a selective inhibitor of phosphodiesterase‐4 involved in various neurological diseases, including stroke. However, the protective… Click to show full abstract
Stroke is a devastating event and a huge public health concern worldwide. Apremilast (APR) is a selective inhibitor of phosphodiesterase‐4 involved in various neurological diseases, including stroke. However, the protective effects of APR on stroke have not been investigated. Here, we explored the effects of APR on stroke outcomes and blood–brain barrier (BBB) dysfunction using a middle cerebral artery occlusion (MCAO) stroke mice model.
Keywords:
protective effects;
blood brain;
brain barrier;
brain;
outcomes blood;
stroke outcomes
Journal Title: Brain and Behavior
Year Published: 2022
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Journal Title: Brain and Behavior
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!