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Neuropsychiatric Inventory domains cluster into neuropsychiatric syndromes in Alzheimer's disease: A systematic review and meta‐analysis

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Background: Studies of patients with Alzheimer's disease (AD) have observed that neuropsychiatric symptoms (NPS) tend to co‐occur as neuropsychiatric syndromes and have generally shown mixed results regarding the number and… Click to show full abstract

Background: Studies of patients with Alzheimer's disease (AD) have observed that neuropsychiatric symptoms (NPS) tend to co‐occur as neuropsychiatric syndromes and have generally shown mixed results regarding the number and composition of syndromes. We systematically reviewed how neuropsychiatric syndromes in AD have been defined and compared the different published definitions in a pooled sample of AD patients using meta‐analytic structural equation modeling (MASEM).

Keywords: domains cluster; alzheimer disease; inventory domains; neuropsychiatric inventory; neuropsychiatric syndromes

Journal Title: Brain and Behavior
Year Published: 2022

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