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Midazolam alleviates cellular senescence in SH‐SY5Y neuronal cells in Alzheimer's disease

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Alzheimer's disease (AD) impacts the daily life of aging people. Oligomerized amyloid β (Aβ)‐associated neuronal senescence is involved in the pathological mechanism of AD. Blockage of neuronal senescence has been… Click to show full abstract

Alzheimer's disease (AD) impacts the daily life of aging people. Oligomerized amyloid β (Aβ)‐associated neuronal senescence is involved in the pathological mechanism of AD. Blockage of neuronal senescence has been considered an important strategy for the treatment of AD. Midazolam is a hypnotic‐sedative drug with pleiotropic properties.

Keywords: midazolam alleviates; senescence; alzheimer disease; alleviates cellular

Journal Title: Brain and Behavior
Year Published: 2022

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