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Exogenous recombinant Hsp70 attenuates sevoflurane anesthesia‐induced cognitive dysfunction in aged mice

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Postoperative cognitive dysfunction (POCD) is a severe postoperative neurological sequela in elderly patients, and there is currently no standard treatment for POCD. In this study, whether recombinant human heat shock… Click to show full abstract

Postoperative cognitive dysfunction (POCD) is a severe postoperative neurological sequela in elderly patients, and there is currently no standard treatment for POCD. In this study, whether recombinant human heat shock protein 70 (rHsp70) could alleviate sevoflurane‐induced cognitive impairment in aged mice is investigated.

Keywords: cognitive dysfunction; induced cognitive; aged mice; exogenous recombinant; recombinant hsp70

Journal Title: Brain and Behavior
Year Published: 2022

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