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The core of maintaining neuropathic pain: Crosstalk between glial cells and neurons (neural cell crosstalk at spinal cord)

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Neuropathic pain (NP) caused by the injury or dysfunction of the nervous system is a chronic pain state accompanied by hyperalgesia, and the available clinical treatment is relatively scarce. Hyperalgesia… Click to show full abstract

Neuropathic pain (NP) caused by the injury or dysfunction of the nervous system is a chronic pain state accompanied by hyperalgesia, and the available clinical treatment is relatively scarce. Hyperalgesia mediated by pro‐inflammatory factors and chemokines plays an important role in the occurrence and maintenance of NP.

Keywords: maintaining neuropathic; pain crosstalk; core maintaining; crosstalk glial; neuropathic pain; pain

Journal Title: Brain and Behavior
Year Published: 2023

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