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microRNA‐221 rescues the loss of dopaminergic neurons in a mouse model of Parkinson's disease

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Parkinson's disease (PD) is one of the most common systemic neurodegenerative diseases and is related to the loss of dopaminergic neurons in the substantia nigra. Several studies verified that microRNA… Click to show full abstract

Parkinson's disease (PD) is one of the most common systemic neurodegenerative diseases and is related to the loss of dopaminergic neurons in the substantia nigra. Several studies verified that microRNA (miRNAs) targeting the Bim/Bax/caspase‐3 signaling axis is involved in the apoptosis of dopaminergic neurons in substantia nigra. In this study, we aimed to explore the role of miR‐221 in PD.

Keywords: loss dopaminergic; parkinson disease; dopaminergic neurons

Journal Title: Brain and Behavior
Year Published: 2023

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