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Challenges and opportunities of diagnostic markers of Alzheimer's disease based on structural magnetic resonance imaging

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This article aimed to carry out a narrative literature review of early diagnostic markers of Alzheimer's disease (AD) based on both micro and macro levels of pathology, indicating the shortcomings… Click to show full abstract

This article aimed to carry out a narrative literature review of early diagnostic markers of Alzheimer's disease (AD) based on both micro and macro levels of pathology, indicating the shortcomings of current biomarkers and proposing a novel biomarker of structural integrity that associates the hippocampus and adjacent ventricle together. This could help to reduce the influence of individual variety and improve the accuracy and validity of structural biomarker.

Keywords: markers alzheimer; alzheimer disease; disease based; challenges opportunities; diagnostic markers

Journal Title: Brain and Behavior
Year Published: 2023

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