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MxA mRNA decrease preceding NAb detection in IFNβ‐treated MS patients

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Multiple sclerosis (MS) patients treated with interferon beta (IFNβ) are at risk of a declining response to treatment because of the production of IFNβ‐neutralizing antibodies (NAbs). The expression of Myxovirus… Click to show full abstract

Multiple sclerosis (MS) patients treated with interferon beta (IFNβ) are at risk of a declining response to treatment because of the production of IFNβ‐neutralizing antibodies (NAbs). The expression of Myxovirus resistance protein A (MxA) mRNA is regarded as a marker of IFNβ bioactivity.

Keywords: preceding nab; mxa mrna; ifn; decrease preceding; mrna decrease; nab detection

Journal Title: Brain and Behavior
Year Published: 2017

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