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Multiplex Immunofluorescent Batch Labeling of Marmoset Brain Sections

The common marmoset is a small nonhuman primate that has emerged as a valuable animal model in neuroscience research. Accurate analysis of brain tissue is crucial to understand marmoset neurophysiology… Click to show full abstract

The common marmoset is a small nonhuman primate that has emerged as a valuable animal model in neuroscience research. Accurate analysis of brain tissue is crucial to understand marmoset neurophysiology and to model neurodegenerative diseases. Many studies to date have complemented magnetic resonance imaging (MRI) with histochemical staining rather than immunofluorescent labeling, which can generate more informative and higher resolution images. There is a need for high‐throughput immunolabeling and imaging methodologies to generate resources for the burgeoning marmoset field, particularly brain histology atlases to display the organization of different cell types and other structures.

Keywords: labeling marmoset; brain; marmoset; batch labeling; immunofluorescent batch; multiplex immunofluorescent

Journal Title: Brain and Behavior
Year Published: 2025

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