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Linking Psychotic‐Like Experiences and Brain White Matter Microstructure in Young Women

Psychotic‐like experiences (PLE) represent a risk factor for later psychotic disorders and a marker for general mental distress. The connectivity and microstructure of key brain white matter pathways, including fronto–temporal… Click to show full abstract

Psychotic‐like experiences (PLE) represent a risk factor for later psychotic disorders and a marker for general mental distress. The connectivity and microstructure of key brain white matter pathways, including fronto–temporal trajectories, have been implicated in psychosis and psychosis‐risk. Although sex differences in PLE prevalence and characteristics have been reported, most neuroimaging studies of PLE have primarily included mixed‐sex, samples and little research has been carried out in females only. This study examines the associations between PLE and white matter characteristics in young to middle‐aged females.

Keywords: white matter; brain; psychotic like; brain white; like experiences

Journal Title: Brain and Behavior
Year Published: 2025

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