St. John's wort (Hypericum perforatum) has been used for centuries as a medicinal plant to remedy external disorders such as burns and wounds, as well as internal disorders such as… Click to show full abstract
St. John's wort (Hypericum perforatum) has been used for centuries as a medicinal plant to remedy external disorders such as burns and wounds, as well as internal disorders such as nerve pain, anxiety, and depression. Bone marrow mesenchymal stem cells (BMSCs) are a heterogeneous population of pluripotent stromal cells that can differentiate into a variety of cell types. The aim of the study was to individually and combinationally investigate the effect of whole extract and stem cells on Parkinson's disease. Furthermore, using a new method for stem cells transplantation to enhance cell integration into substantia nigra pars compacta (SNC) and striatum.
Journal Title: Brain and behavior
Year Published: 2025
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